A Software Environment for DNA Sequence Assembly
We have continued the development of a prototype software environment
in support of DNA sequencing called "FAKtory". The environment consists
of (1) Gene Myers' software library, FAK II, for the core combinatorial
problem of assembling fragments, (2) a Tcl/Tk based interface, and (3)
a software suite supporting a database of fragments and a processing
pipeline that includes clipping, tagging, and vector removal modules. A
key feature of FAKtory is that it is highly customizable: the structure
of the fragment database, the processing pipeline, and the operation of
each phase of the pipeline are specifiable by the user. Yet such
customization need only be established once at a given site,
subsequently users see a relatively simple system tailored to their
needs.
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